Cannabinoid Receptor 1
A cannabinoid receptor antagonist, also known simply as a cannabinoid antagonist or as an anticannabinoid, is a type of cannabinoidergic drug that binds to cannabinoid receptors (CBR) and prevents their activation by endocannabinoids. They include antagonists, inverse agonists, and antibodies of CBRs. The discovery of the endocannabinoid system led to the development of CB1 receptor antagonists.
Cannabinoid Receptor 2
Cannabinoid receptors are of a class of cell membrane receptors under the G protein-coupled receptor superfamily. Cannabinoid receptors are activated by three major groups of ligands: endocannabinoids, produced by the mammillary body; plant cannabinoids (such as Cannabidiol, produced by the cannabis plant); and synthetic cannabinoids (such as HU-210). All of the endocannabinoids and plant cannabinoids are lipophilic, such as fat soluble compounds.
Camphene, a plant-derived monoterpene, emits pungent odors of damp woodlands and fir needles. Camphene may play a critical role in cardiovascular disease.
The Vallianou et al study found camphene reduces plasma cholesterol and triglycerides in hyperlipidemic rats. Given the importance that the control of hyperlipidemia plays in heart disease, the results of this study provide insight into to how camphene might be used as an alternative to pharmaceutical lipid lowering agents which are proven to cause intestinal problems, liver damage and muscle inflammation. This finding alone warrants further investigation.
Camphene is a minor component of many essential oils such as turpentine, camphor oil, citronella oil and ginger oil. It is used as a food additive for flavoring, and also used in the preparation of fragrances. It is produced industrially by catalytic isomerization of the more common α-pinene.
What Is Camphene And How Is It Used?
Camphene is a crystalline solid that is usually colorless, or white, that comes with a notable odor that is camphor like in nature. The dust and the crystals can be irritating to the nose, eyes and throat. However, this is a substance that is soluble in some general organic solvents, and it can also vaporize when at room temperature. This is something that you will often see as a main constituent in things like cypress oil, neroli, camphor oil, valerian, ginger oil and citronella oil.
On a commercial level, camphene is usually used as a kind of food additive or a main ingredient for the production of various fragrances. This is a substance that is very similar to that of camphor in terms of fragrance. When camphene is heated up, the crystals will give off vapors and it is also known for use in the production of manmade camphor and insecticides.
Today, there are a number of therapeutic properties of camphene, including:
Antifungal Properties – Camphene and camphor with the sage essential oil can be used for antifungal properties. You can use it for the treatment of dysentery, fungal skin infections, dermatitis and athlete’s foot.
Cytotoxic/Antibiotic Properties – With a mixture of cineole, eugenol and camphene in tulsi oil, you can treat a number of fungal, bacterial and viral infections that are known to impact the respiratory system. This is a mixture that is wonderful for helping to cure congestion and it can treat some of the more severe respiratory disorders such as bronchitis. The active ingredients that are found in tulsi oil can be used to help treat some of the damage to the lungs that is caused by tuberculosis and cancer from smoking.
The camphene that is found in holy basil can be used directly onto the skin as a paste or an oil extract for antibacterial treatment. You can also use the extract as a way to create a cooling feeling on skin that is irritated or as a handy way to keep bugs away when you are enjoying the outdoors.
Not only does camphene have the properties listed, but you can also use it to treat other conditions such as hyperlipidemia and allergies. Camphene when mixed with vitamin C is also a powerful antioxidant that can help with a soothing effect on the nerves and stress. Overall, this is a worthy ingredient used by many in the natural health world.